| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PDGFC |
| Specificity: |
This antibody reacts specifically with PDGFC |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PDGFC/VEGF E |
| Gene ID: |
56034 |
| Swiss Prot: |
Q9NRA1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In the nucleus, Involved in fibrotic processes, PDGFC seems to have additional function, Plays an important role in angiogenesis and blood vessel development, Plays an important role in wound healing, Potent mitogen and chemoattractant for cells of mesenchymal origin, Required for normal skeleton formation during embryonic development, Required for normal skin morphogenesis during embryonic development, The CUB domain has mitogenic activity in coronary artery smooth muscle cells, cell migration, cell proliferation, especially for normal development of the craniofacial skeleton and for normal development of the palate, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs, proliferation and remodeling, suggesting a role beyond the maintenance of the latency of the PDGF domain, survival and chemotaxis, where it appears to be involved in three stages: inflammation, Growth factor that plays an essential role in the regulation of embryonic development |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SCDGF fallotein |
| Also known as: |
PDGFC Polyclonal Antibody |
| Other name: |
Anti-PDGFC Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PDGFC |
| Short name: |
Anti-PDGFC (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-platelet derived growth factor C (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
PDGFC and IDBG-42546 and ENSG00000145431 and 56034, PDGFC and IDBG-630627 and ENSBTAG00000043959 and 613787, Pdgfc and IDBG-153854 and ENSMUSG00000028019 and 54635, nuclei, protein homodimerization activity, this GO :0000139 and this GO lgi membrane and cellular component this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007417 and central nervous system development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0042803 and protein homodimerization activity and molecular function this GO :0045740 and positive regulation of DNA replication and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0050730 and regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071230 and cellular response to amino acid stimulus and biological process, this GO :0005161 : platelet-derived growth factor receptor binding, this GO :0005161 : platelet-derived growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0042803 : protein homodimerization activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0042803 : protein homodimerization activity, platelet derived growth factor C |
| Identity: |
8801 |
| Gene: |
PDGFC |
More about : PDGFC |
| Long gene name: |
platelet derived growth factor C |
| Locus: |
4q32, 1 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
AF091434 |
| Entrez gene record: |
56034 |
| Pubmed identfication: |
10858496 |
| Havana BLAST/BLAT: |
OTTHUMG00000161803 |