| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MATK |
| Specificity: |
This antibody reacts specifically with MATK |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MATK |
| Gene ID: |
4145 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is able to phosphorylate and inactivate Src family kinases, MATK is thought to play a significant role in the signal transduction of hematopoietic cells, This protein might be involved in signaling in some cases of breast cancer, a catalytic domain, a unique N terminus, and lack of an autophosphorylation site, and may play an inhibitory role in the control of T-cell proliferation, lack of a negative regulatory phosphorylation site, lack of myristylation signals, The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HYLTK CTK HYL Lsk CHK HHYLTK DKFZp434N1212 MGC1708 MGC2101 |
| Also known as: |
MATK Polyclonal Antibody |
| Other name: |
Anti-MATK Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MATK |
| Short name: |
Anti-MATK (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MATK (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6906 |
| Gene: |
MATK |
More about : MATK |
| Long gene name: |
megakaryocyte-associated tyrosine kinase |
| Synonyms name: |
Csk-homologous kinase tyrosine-protein kinase CTK protein kinase HYL hematopoietic consensus tyrosine-lacking kinase tyrosylprotein kinase hydroxyaryl-protein kinase Csk-type protein tyrosine kinase HYL tyrosine kinase tyrosine kinase MATK leukocyte carboxyl-terminal src kinase related |
| Locus: |
19p13, 3 |
| Discovery year: |
1994-07-22 |
| GenBank acession: |
L18974 |
| Entrez gene record: |
4145 |
| Pubmed identfication: |
8288563 7530249 |
| RefSeq identity: |
NM_139355 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180916 |