| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NFKB p65 Thr435 |
| Specificity: |
This antibody reacts specifically with NFKB p65(Thr435) |
| Modification: |
Phosphorylation |
| Modification site: |
Thr435 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human NFKBp65 around the phosphorylation site of Thr435 |
| Gene ID: |
5970 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Four transcript variants encoding different isoforms have been found for this gene, It is held in the cytoplasm in an inactive state by specific inhibitors, NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, NF-kappa-B moves to the nucleus and activates transcription of specific genes, RELA, RELA, Sep 2011], The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, Upon degradation of the inhibitor, [provided by RefSeq, or RELB, NF-kappa-B is a ubiquitous transcription factor involved in several biological processes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Avian reticuloendotheliosis viral v rel oncogene homolog A, MGC131774, NF-Î, NFKB 3, NFKB3, NFKBp65, NFKBp65, Nuclear Factor NF Kappa B p65 Subunit, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3, RELA, RELAphospho T435, Transcription Factor p65, V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A, p65 NF kappaB, p65 NFkB, p65NFKB, v rel avian reticuloendotheliosis viral oncogene homolog A nuclear factor of kappa light polypeptide gene enhancer in B cells 3 p65, v rel reticuloendotheliosis viral oncogene homolog A avian, v-rel reticuloendotheliosis viral oncogene homolog A, º, Bp65, NFkB-p65Thr435 |
| Also known as: |
NFKB p65(Thr435) Polyclonal Antibody |
| Other name: |
Anti-NFKB p65(Thr435) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NFKB p65(Thr435) |
| Short name: |
Anti-NFKB p65(Thr435) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NFKB p65(Thr435) (polyclonal) |
| Alternative technique: |
polyclonals |