| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SNAI2 Ser155+Ser158+Ser160+Tyr163+Tyr168 |
| Specificity: |
This antibody reacts specifically with SNAI2(Ser155+Ser158+Ser160+Tyr163+Tyr168) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser155+Ser158+Ser160+Tyr163+Tyr168 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human SNAI2 around the phosphorylation site of Ser155+Ser158+Ser160+Tyr164+Tyr169 |
| Gene ID: |
6591 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Mutations in this gene may be associated with sporadic cases of neural tube defects (referenced from Entrez gene), SLUG also has antiapoptotic activity, SLUG is involved in epithelial-mesenchymal transitions (EMT) involving E-cadherin repression which is known to play an important role in tumor progression amd neural tube formation, The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin, SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SLUGH1 SNAIL2 SLUGH |
| Also known as: |
SNAI2(Ser155+Ser158+Ser160+Tyr163+Tyr168) Antibody |
| Other name: |
Anti-SNAI2(Ser155+Ser158+Ser160+Tyr163+Tyr168) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
SNAI2(Ser155+Ser158+Ser160+Tyr163+Tyr168) |
| Short name: |
Anti-SNAI2(Ser155+Ser158+Ser160+Tyr163+Tyr168) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SNAI2(Ser155+Ser158+Ser160+Tyr163+Tyr168) |
| Identity: |
11094 |
| Gene: |
SNAI2 |
More about : SNAI2 |
| Long gene name: |
snail family transcriptional repressor 2 |
| Synonyms gene: |
SLUG |
| Synonyms gene name: |
slug homolog, zinc finger protein (chicken) snail homolog 2 (Drosophila) snail family zinc finger 2 |
| Locus: |
8q11, 21 |
| Discovery year: |
1998-07-03 |
| GenBank acession: |
U97060 |
| Entrez gene record: |
6591 |
| Pubmed identfication: |
9337409 9721220 |
| RefSeq identity: |
NM_003068 |
| Classification: |
Zinc fingers C2H2-type SNAG transcriptional repressors |
| Havana BLAST/BLAT: |
OTTHUMG00000149912 |