| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CDK6 Tyr24 |
| Specificity: |
This antibody reacts specifically with CDK6 (Tyr24) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr24 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human CDK6 around the phosphorylation site of Tyr24 |
| Gene ID: |
1021 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, The activity of this kinase first appears in mid-G1 phase, This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors, The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PLSTIRE |
| Also known as: |
CDK6 (Tyr24) Polyclonal Antibody |
| Other name: |
Anti-CDK6 (Tyr24) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CDK6 (Tyr24) |
| Short name: |
Anti-CDK6 (Tyr24) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CDK6 (Tyr24) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1777 |
| Gene: |
CDK6 |
More about : CDK6 |
| Long gene name: |
cyclin dependent kinase 6 |
| Locus: |
7q21, 2 |
| Discovery year: |
1994-02-14 |
| Entrez gene record: |
1021 |
| Pubmed identfication: |
1639063 |
| Classification: |
Cyclin dependent kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000131697 |
| Locus Specific Databases: |
LRG_991 |