| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Cofilin Tyr140 |
| Specificity: |
This antibody reacts specifically with Cofilin (Tyr140) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr140 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Intracellular |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Cofilin around the phosphorylation site of Tyr140 |
| Gene ID: |
1072 |
| Swiss Prot: |
P23528 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Important for normal progress through mitosis and normal cytokinesis, Plays a role in the regulation of cell morphology and cytoskeletal organization, Regulates actin cytoskeleton dynamics, Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation, Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
18 kDa phosphoprotein, CFL1, Cofilin, Cofilin-1, HEL-S-15, cofilin, non-muscle isoform, p18, CFL |
| Also known as: |
Cofilin (Tyr140) Polyclonal Antibody |
| Other name: |
Anti-Cofilin (Tyr140) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Cofilin (Tyr140) |
| Short name: |
Anti-Cofilin (Tyr140) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cofilin (Tyr140) (polyclonal) |
| Alternative technique: |
polyclonals |