| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Amyloid Precursor Protein Ser198 |
| Specificity: |
This antibody reacts specifically with Amyloid Precursor Protein(S198) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser198 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from mouse APP around the phosphorylation site of Ser198 |
| Gene ID: |
351 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Jul 2008], Multiple transcript variants encoding several different isoforms have been found for this gene, Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy), Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, [provided by RefSeq, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease, This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
A4, A4 amyloid protein, A4_HUMAN, AAA, ABETA, ABPP, AD 1, AD1, APP, APP I , APP Ser198, APPI, Alzheimer disease, Alzheimer disease 1, Alzheimer's disease amyloid protein, Amyloid Precursor Protein phospho Ser198, Amyloid beta A4 precursor protein, Amyloid beta A4 protein, Amyloid beta A4 protein precursor isoform a, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform c, Amyloid beta A4 protein precursor isoform c, Amyloid beta protein, Amyloid beta-peptide, Amyloid of aging and alzheimer disease, Beta amyloid peptide, CTFgamma, CVAP, Cerebral vascular amyloid peptide, Human mRNA for amyloid A4 precursor of Alzheimer's disease, PN 2, PN II, PN2, PreA4, Protease nexin II, Soluble APP-alpha, Soluble APP-beta, p-APPSer198, p-Amyloid Precursor Protein phospho S198, Amyloid Precursor Protein phospho S198 |
| Also known as: |
Amyloid Precursor Protein(S198) Antibody |
| Other name: |
Anti-Amyloid Precursor Protein(S198) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Description: |
also called a , is a type of partially differentiated, usually , Precursor cell, blast, blast cell , cell that has lost most or all of the , multipotency, or simply , stem cell , unipotent |
| Gene target: |
Amyloid Precursor Protein(S198) |
| Short name: |
Anti-Amyloid Protein(S198) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Amyloid Precursor Protein(S198) |