| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Ceramide synthase 2 |
| Specificity: |
This antibody reacts specifically with Ceramide synthase 2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Lumenal |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Ceramide synthase 2 |
| Gene ID: |
29956 |
| Swiss Prot: |
Q96G23 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells, Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, It is thought to be involved in sphingolipid synthesis, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids, LASS2 (LAG1 homolog |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SP260 FLJ10243 |
| Also known as: |
Ceramide synthase 2 Polyclonal Antibody |
| Other name: |
Anti-Ceramide synthase 2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Ceramide synthase 2 |
| Short name: |
Anti-Ceramide synthase 2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Ceramide synthase 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14076 |
| Gene: |
CERS2 |
More about : CERS2 |
| Long gene name: |
ceramide synthase 2 |
| Synonyms gene: |
LASS2 |
| Synonyms gene name: |
S, ceramide synthase 2 , cerevisiae) LAG1 homolog, cerevisiae) homolog 2 LAG1 longevity assurance homolog 2 (S, longevity assurance (LAG1 |
| Locus: |
1q21, 3 |
| Discovery year: |
2001-09-10 |
| GenBank acession: |
AF189062 |
| Entrez gene record: |
29956 |
| Pubmed identfication: |
11543633 |
| RefSeq identity: |
NM_022075 |
| Classification: |
CERS class homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000035064 |