| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ACOT8 |
| Specificity: |
This antibody reacts specifically with ACOT8 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ACOT8 |
| Gene ID: |
10005 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acyl-coenzyme A Thioesterase 8, It is a major thioesterase in peroxisomes and competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA), It shows a preference for medium-length fatty acyl-CoAs and may be involved in the metabolic regulation of peroxisome proliferation, also known as ACOT8 may mediate Nef-induced down-regulation of CD4, free fatty acids and CoASH, providing the potential to regulate intracellular levels of acyl-CoAs, Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
hACTE-III hTE PTE-2 NAP1 |
| Also known as: |
ACOT8 Polyclonal Antibody |
| Other name: |
Anti-ACOT8 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ACOT8 |
| Short name: |
Anti-ACOT8 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ACOT8 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
15919 |
| Gene: |
ACOT8 |
More about : ACOT8 |
| Long gene name: |
acyl-CoA thioesterase 8 |
| Synonyms gene: |
PTE1 |
| Synonyms gene name: |
peroxisomal acyl-CoA thioesterase peroxisomal acyl-CoA thioesterase 1 |
| Synonyms name: |
choloyl-CoA hydrolase Nef (lentivirus myristoylated factor) associated protein 1 |
| Locus: |
20q13, 12 |
| Discovery year: |
2001-08-01 |
| GenBank acession: |
AF014404 |
| Entrez gene record: |
10005 |
| Pubmed identfication: |
10092594 9153233 16103133 16940157 |
| RefSeq identity: |
NM_183386 |
| Classification: |
Acyl-CoA thioesterases |
| Havana BLAST/BLAT: |
OTTHUMG00000033045 |