| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ERAS/HRAS2 |
| Specificity: |
This antibody reacts specifically with ERAS/HRAS2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ERAS/HRAS2 |
| Gene ID: |
3266 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, Ras family, Ras proteins bind GDP/GTP and possess intrinsic GTPase activity, The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase, ERAS belongs to the small GTPase superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ERAS/HRAS2 Polyclonal Antibody |
| Other name: |
Anti-ERAS/HRAS2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ERAS/HRAS2 |
| Short name: |
Anti-ERAS/HRAS2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ERAS/HRAS2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5174 |
| Gene: |
ERAS |
More about : ERAS |
| Long gene name: |
ES cell expressed Ras |
| Synonyms gene: |
HRAS2 HRASP |
| Synonyms gene name: |
v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene |
| Locus: |
Xp11, 23 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X00419 |
| Entrez gene record: |
3266 |
| Pubmed identfication: |
12774123 |
| RefSeq identity: |
NM_181532 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000059533 |