| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Factor VII |
| Specificity: |
This antibody reacts specifically with Factor VII |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Factor VII heavy chain |
| Gene ID: |
2155 |
| Swiss Prot: |
P08709 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Factor VII is converted to factor VIIa by factor Xa, Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium, In the presence of tissue factor and calcium ions, Serine protease that circulates in the blood in a zymogen form, factor IXa, factor VIIa then converts factor X to factor Xa by limited proteolysis, factor XIIa, or thrombin by minor proteolysis, Initiates the extrinsic pathway of blood coagulation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Factor VII Polyclonal Antibody |
| Other name: |
Anti-Factor VII Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Factor VII |
| Short name: |
Anti-Factor VII (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Factor VII (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3544 |
| Gene: |
F7 |
More about : F7 |
| Long gene name: |
coagulation factor VII |
| Synonyms gene name: |
coagulation factor VII (serum prothrombin conversion accelerator) |
| Synonyms name: |
eptacog alfa FVII coagulation protein factor VII |
| Locus: |
13q34 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2155 |
| Pubmed identfication: |
3264725 2511201 |
| RefSeq identity: |
NM_000131 |
| Classification: |
Gla domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000017373 |
| Locus Specific Databases: |
LRG_554 |