| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HSPB2 |
| Specificity: |
This antibody reacts specifically with HSPB2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HSPB2 |
| Gene ID: |
3316 |
| Swiss Prot: |
Q16082 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
HSPB2 (heat shock 27 kDa protein 2), HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death, HSPB2 is abundantly expressed in several cancer cell lines, Localized to mitochondria, abundantly expressed proteins with diverse functions, also known as HSP 27 or MKBP, including the assembly and sequestering of multi-protein complexes, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle, suggesting that HSPB2 may be an important factor in tumor transformation and metastasis, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding, The heat shock proteins (HSPs) comprise a group of highly conserved |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Hs, 78846 MKBP |
| Also known as: |
HSPB2 Polyclonal Antibody |
| Other name: |
Anti-HSPB2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HSPB2 |
| Short name: |
Anti-HSPB2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-HSPB2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5247 |
| Gene: |
HSPB2 |
More about : HSPB2 |
| Long gene name: |
heat shock protein family B (small) member 2 |
| Synonyms gene name: |
heat shock 27kD protein 2 heat shock 27kDa protein 2 |
| Locus: |
11q23, 1 |
| Discovery year: |
1997-12-23 |
| GenBank acession: |
U75898 |
| Entrez gene record: |
3316 |
| Pubmed identfication: |
9344664 9490724 |
| Classification: |
Small heat shock proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000166886 |