| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Uteroglobin |
| Specificity: |
This antibody reacts specifically with Uteroglobin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Uteroglobin |
| Gene ID: |
1390 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994, Decreased CC16 concentrations were also found in the amniotic fluid of fetuses suffering from pulmonary hypoplasia caused by various mechanisms (diaphragmatic hernia, Decreased serum CC16 levels are found after pulmonary resection, In pleural effusions, In serum, It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction, Th2 lymphocyte regulation, There is convincing data suggesting it has phospholipase A2 inhibitory activity, Turner and Down syndrome), a number of other immunomodulatory features including inhibition of interferon gamma signalling and Th1 vs, as well as, asbestos, diabetic fetopathy, in silica-exposed workers, its increase is associated with age, nitrogen chloride and ozone exposure, sarcoidosis and high PEEP ventilation, smokers and in asthma, the CC16 concentration appears to be associated with its diffusion from the lung as evidenced by high CC16 levels in cardiac pleural congestion, Uteroglobin belongs to the family of secretoglobins and is a secreted protein product of nonciliated bronchiolar Clara cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CC10 CCSP CC16 |
| Also known as: |
Uteroglobin Polyclonal Antibody |
| Other name: |
Anti-Uteroglobin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Uteroglobin |
| Short name: |
Anti-Uteroglobin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Uteroglobin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12523 |
| Gene: |
SCGB1A1 |
More about : SCGB1A1 |
| Long gene name: |
secretoglobin family 1A member 1 |
| Synonyms gene: |
UGB |
| Synonyms gene name: |
uteroglobin |
| Synonyms name: |
Uteroglobin (Clara-cell specific 10-kD protein) |
| Locus: |
11q12, 3 |
| Discovery year: |
1992-11-03 |
| Entrez gene record: |
7356 |
| Pubmed identfication: |
1284526 22155607 |
| RefSeq identity: |
NM_003357 |
| Classification: |
Secretoglobins |
| Havana BLAST/BLAT: |
OTTHUMG00000167526 |