| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
c-Jun Thr91+Thr93 |
| Specificity: |
This antibody reacts specifically with c-Jun(Thr91+Thr93) |
| Modification: |
Phosphorylation |
| Modification site: |
Thr91+Thr93 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of (Thr91+Thr93) |
| Gene ID: |
3725 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Extracellular signals including growth factors, In addition, Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways, SAPK/JNK, The MAP kinase homologue, The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription, C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AP 1, AP-1, AP1, Activator 1, Activator Protein 1, Enhancer Binding Protein AP1, JUN, JUN protein, JUNC, JUN_HUMAN, Jun Activation Domain Binding Protein, Jun oncogene, Proto oncogene cJun, Proto-oncogene c-Jun, Transcription Factor AP1, Transcription factor AP-1, V jun avian sarcoma virus 17 oncogene homolog, V-jun avian sarcoma virus 17 oncogene homolog, c-Jun phospho T91+T93, c-Jun phospho Thr91+Thr93, p-c-Jun Thr93, p39, vJun Avian Sarcoma Virus 17 Oncogene Homolog, p-c-JunThr91+Thr93 |
| Also known as: |
c-Jun(Thr91+Thr93) Polyclonal Antibody |
| Other name: |
Anti-c-Jun(Thr91+Thr93) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
c-Jun(Thr91+Thr93) |
| Short name: |
Anti-c-Jun(Thr91+Thr93) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-c-jun proto-oncogene(Thr91+Thr93) (polyclonal) |
| Alternative technique: |
polyclonals |