| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PPAR Gamma |
| Specificity: |
This antibody reacts specifically with PPAR Gamma |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PPAR Gamma |
| Gene ID: |
5468 |
| Swiss Prot: |
P37231 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer, Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses, It therefore controls the peroxisomal beta-oxidation pathway of fatty acids, Key regulator of adipocyte differentiation and glucose homeostasis, Once activated by a ligand, Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity), such as acyl-CoA oxidase, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
hPPAR NR1C1 |
| Also known as: |
PPAR Gamma Polyclonal Antibody |
| Other name: |
Anti-PPAR Gamma Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PPAR Gamma |
| Short name: |
Anti-PPAR Gamma (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PPAR g (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9232 |
| Gene: |
PPARA |
More about : PPARA |
| Long gene name: |
peroxisome proliferator activated receptor alpha |
| Synonyms gene: |
PPAR |
| Synonyms gene name: |
alpha peroxisome proliferator-activated receptor alpha , peroxisome proliferative activated receptor |
| Locus: |
22q13, 31 |
| Discovery year: |
1993-11-01 |
| GenBank acession: |
L02932 |
| Entrez gene record: |
5465 |
| Pubmed identfication: |
7684926 10591208 |
| RefSeq identity: |
NM_001001928 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000150443 |