| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TPX2 |
| Specificity: |
This antibody reacts specifically with TPX2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TPX2 |
| Gene ID: |
22974 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is also critical for the function of protein kinase Aurora A, TPX2 autophosphorylates Aurora A, TPX2 has also been found to be highly expressed in cancer cells, playing a role in the S and G2 phases of mitosis, targeting it to the spindle apparatus and allowing it to function in eukaryotic meiotic and mitotic cell cycles, TPX2 is essential for spindle pole and mitotic spindle formulation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
p100 DIL-2 |
| Also known as: |
TPX2 Polyclonal Antibody |
| Other name: |
Anti-TPX2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TPX2 |
| Short name: |
Anti-TPX2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, homolog (Xenopus laevis) (polyclonal), microtubule-associated, antibody to-TPX2 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, C20orf1 and C20orf2 and DIL-2 and DIL2 and FLS353 and GD:C20orf1 and HCA519 and HCTP4 and p100 and REPP86, TPX2 and IDBG-63816 and ENSG00000088325 and 22974, Tpx2 and IDBG-209892 and ENSMUSG00000027469 and 72119, homolog (Xenopus laevis), microtubule-associated, nuclei, protein kinase binding, this GO :0000922 and spindle pole and cellular component this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0005874 and microtubule and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0008283 and cell proliferation and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0032147 and activation of protein kinase activity and biological process this GO :0043203 and axon hillock and cellular component this GO :0060236 and regulation of mitotic spindle organization and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005525 : GTP binding and also this GO :0019901 : protein kinase binding, this GO :0005524 : ATP binding, this GO :0005525 : GTP binding, this GO :0019901 : protein kinase binding, 28741 and IDBG-641544 and ENSBTAG00000018775 and 507226, TPX2 |
| Identity: |
1249 |
| Gene: |
TPX2 |
More about : TPX2 |
| Long gene name: |
TPX2, microtubule nucleation factor |
| Synonyms gene: |
C20orf2 C20orf1 |
| Synonyms gene name: |
chromosome 20 open reading frame 1 TPX2, homolog (Xenopus laevis) TPX2, microtubule-associated, microtubule-associated |
| Locus: |
20q11, 21 |
| Discovery year: |
1999-09-29 |
| GenBank acession: |
AF098158 |
| Entrez gene record: |
22974 |
| Pubmed identfication: |
9207457 10393424 |
| Havana BLAST/BLAT: |
OTTHUMG00000032190 |