| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CDKN2C |
| Specificity: |
This antibody reacts specifically with CDKN2C |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CDKN2C |
| Gene ID: |
1031 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Highest expression levels are found in skeletal muscle, It is maximally induced as cells enter S phase, and is expressed during G1 to S transition in the eukaryotic cell division cycle, but it is also found in the pancreas and heart, p18 INK4c is a specific inhibitor of cdk4 / cdk6 (it interacts strongly with CDK6 and weakly with CDK4) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
INK4C p18 |
| Also known as: |
CDKN2C Polyclonal Antibody |
| Other name: |
Anti-CDKN2C Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CDKN2C |
| Short name: |
Anti-CDKN2C (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, inhibits cyclin-dependent kinase 4) (polyclonal), antibody to-cyclin-dependent kinase inhibitor 2C (p18 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CDKN2C and IDBG-639655 and ENSBTAG00000011059 and 505691, CDKN2C and IDBG-98423 and ENSG00000123080 and 1031, Cdkn2c and IDBG-174648 and ENSMUSG00000028551 and 12580, INK4C and p18 and p18-INK4C, inhibits CDK4), nuclei, protein kinase binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007050 and cell cycle arrest and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0048709 and oli this GO dendrocyte differentiation and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, cyclin-dependent kinase inhibitor 2C (p18 |
| Identity: |
1789 |
| Gene: |
CDKN2C |
More about : CDKN2C |
| Long gene name: |
cyclin dependent kinase inhibitor 2C |
| Synonyms gene name: |
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| Locus: |
1p32, 3 |
| Discovery year: |
1995-07-06 |
| GenBank acession: |
BC000598 |
| Entrez gene record: |
1031 |
| Pubmed identfication: |
8001816 9636670 |
| RefSeq identity: |
NM_001262 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000008046 |