| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SLC29A4 |
| Specificity: |
This antibody reacts specifically with SLC29A4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Helical |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SLC29A4 |
| Gene ID: |
222962 |
| Swiss Prot: |
Q7RTT9 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Does not seem to transport nucleoside and nucleoside analogs such as uridine, Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates, In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption, May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters, May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential, Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, adenosine, and azidothymidine, and nitrobenzylthioinosine, cytidine, dilazep, dipyridamole, dopamine, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, guanosine, in particular during ischemia, inosine, norepinephrine and epinephrine, thymidine, with maximal activity in the pH range 5, 5, 5 to 6, Functions as a polyspecific organic cation transporter |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ34923 ENT4 |
| Also known as: |
SLC29A4 Polyclonal Antibody |
| Other name: |
Anti-SLC29A4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SLC29A4 |
| Short name: |
Anti-SLC29A4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SLC29A4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23097 |
| Gene: |
SLC29A4 |
More about : SLC29A4 |
| Long gene name: |
solute carrier family 29 member 4 |
| Synonyms gene name: |
member 4 , member 4 solute carrier family 29 (equilibrative nucleoside transporter), solute carrier family 29 (nucleoside transporters) |
| Locus: |
7p22, 1 |
| Discovery year: |
2003-10-08 |
| GenBank acession: |
AK075422 |
| Entrez gene record: |
222962 |
| Pubmed identfication: |
12838422 |
| RefSeq identity: |
NM_153247 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000023797 |