| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FANCG |
| Specificity: |
This antibody reacts specifically with FANCG |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FANCG |
| Gene ID: |
2189 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A minimum of 8 FA genes have been identified, FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes, Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus, and early occurrence of malignancies, bone marrow failure, confers resistance to both hygromycin and mitomycin C, including developmental anomalies, involved in Fanconi anemia, FANCG |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FAG |
| Also known as: |
FANCG Polyclonal Antibody |
| Other name: |
Anti-FANCG Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FANCG |
| Short name: |
Anti-FANCG (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, complementation family G (polyclonal), antibody to-Fanconi anemia |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
FAG and XRCC9, FANCG and IDBG-281538 and ENSG00000221829 and 2189, Fancg and IDBG-139854 and ENSMUSG00000028453 and 60534, MGC159566 and IDBG-632863 and ENSBTAG00000015005 and 615352, complementation group G, nuclei, protein binding, this GO :0000075 and cell cycle checkpoint and biological process this GO :0000160 and phosphorelay signal transduction system and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0003684 and damaged DNA binding and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006281 and DNA repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007286 and spermatid development and biological process this GO :0009314 and response to radiation and biological process this GO :0043240 and Fanconi anaemia nuclear complex and cellular component, this GO :0003684 : damaged DNA binding, this GO :0003684 : damaged DNA binding and also this GO :0004871 : signal transducer activity and also this GO :0005515 : protein binding, this GO :0004871 : signal transducer activity, this GO :0005515 : protein binding, Fanconi anemia |
| Identity: |
3588 |
| Gene: |
FANCG |
More about : FANCG |
| Long gene name: |
Fanconi anemia complementation group G |
| Synonyms gene: |
XRCC9 |
| Synonyms name: |
9 X-ray repair complementing defective repair in Chinese hamster cells 9 , DNA repair protein XRCC9 X-ray repair, complementing defective, in Chinese hamster |
| Locus: |
9p13, 3 |
| Discovery year: |
1998-08-26 |
| GenBank acession: |
AJ007669 |
| Entrez gene record: |
2189 |
| Pubmed identfication: |
9256465 9382107 |
| RefSeq identity: |
NM_004629 |
| Classification: |
Fanconi anemia complementation groups |
| Havana BLAST/BLAT: |
OTTHUMG00000019850 |
| Locus Specific Databases: |
Fanconi Anaemia Mutation Database Fanconi anemia database LRG_499 |