| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PKA gamma |
| Specificity: |
This antibody reacts specifically with PKA gamma |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PKA gamma |
| Gene ID: |
5568 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
C beta, C subunit is activated through autophosphorylation and direct phosphorylation at Thr197 by PDK-1, Certain amino acid substitutions make C gamma a distinct member of the cAMP dependent subfamily of protein kinases, PKA is comprised of two dimers of two subunits, PKA mediates diverse cellular mechanisms, R (regulatory) and C (catalytic), Tissue specific expression of C gamma, Two families of R subunit (RI and RII) and three C subunit isoforms (C alpha, When activated by the second messenger cAMP, acting to modulate it in a functionally specific way, and C gamma) have been identified each possessing distinct cAMP binding properties and resulting in different phosphorylation states, and suggest that C gamma may be distinct in its protein substrate specificity or its interaction with the different regulatory subunits, including proliferation, indicates pressure on C gamma during evolution, ion transport, plus gene transcription, regulation of metabolism, PKA (or cAPK) is a cyclic AMP dependent protein kinase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KAPCG_HUMAN, PKA C gamma, PRKACG, Protein kinase cAMP dependent catalytic gamma, Serine threonine protein kinase, KAPG |
| Also known as: |
PKA gamma Polyclonal Antibody |
| Other name: |
Anti-PKA gamma Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PKA gamma |
| Short name: |
Anti-PKA gamma (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PKA g (polyclonal) |
| Alternative technique: |
polyclonals |