| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Cubilin |
| Specificity: |
This antibody reacts specifically with Cubilin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Intracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Cubilin |
| Gene ID: |
8029 |
| Swiss Prot: |
O60494 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ALB, APOA1, Binds to ALB, Binds to LGALS3 at the maternal-fetal interface, GC, Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands, Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, Kappa and lambda-light chains, MB, May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol, SCGB1A1, Serves as important transporter in several absorptive epithelia, TF, TF and SCGB1A1, The binding of all ligands requires calcium, and the GIF-cobalamin complex, by facilitating their uptake, hemoglobin, hemoglobin, high density lipoprotein, including intestine, renal proximal tubules and embryonic yolk sac, vitamin and iron metabolism, Cotransporter which plays a role in lipoprotein |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Cubilin Polyclonal Antibody |
| Other name: |
Anti-Cubilin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Cubilin |
| Short name: |
Anti-Cubilin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cubilin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
44984 |
| Gene: |
CUBNP2 |
More about : CUBNP2 |
| Long gene name: |
cubilin pseudogene 2 |
| Synonyms gene name: |
cubilin (intrinsic factor-cobalamin receptor) pseudogene 2 |
| Locus: |
10q11, 21 |
| Discovery year: |
2013-01-03 |
| Entrez gene record: |
100289280 |
| Havana BLAST/BLAT: |
OTTHUMG00000018078 |