| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SOD3 |
| Specificity: |
This antibody reacts specifically with SOD3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted, Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SOD3 |
| Gene ID: |
6649 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor, SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, SOD1 is found in all eukaryotic species as a homodimeric 32kDa enzyme containing one each of Cu and Zn ion per subunit, SOD3 is a heparin binding multimer of disulfide linked dimers, SOD4 is a copper chaperone for superoxide dismutase(CCS), Several classes of SOD have been identified, The manganese-containing 80kDa tetrameric enzyme SOD2 is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, These include intracellular copper, Zn SOD (EC SOD/SOD3), Zn SOD/SOD1), mitochondrial manganese SOD (Mn SOD/SOD2) and extracellular Cu, primarily expressed in human lungs, the mitochondrial respiratory chain, vessel walls and airways, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase, which specifically delivers Cu to copper/zinc superoxide dismutase, zinc SOD (Cu, Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
EC-SOD |
| Also known as: |
SOD3 Polyclonal Antibody |
| Other name: |
Anti-SOD3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SOD3 |
| Short name: |
Anti-SOD3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SOD3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11181 |
| Gene: |
SOD3 |
More about : SOD3 |
| Long gene name: |
superoxide dismutase 3 |
| Synonyms gene name: |
extracellular , superoxide dismutase 3 |
| Locus: |
4p15, 2 |
| Discovery year: |
1988-05-08 |
| Entrez gene record: |
6649 |
| Havana BLAST/BLAT: |
OTTHUMG00000128565 |