| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
cGMP |
| Specificity: |
this antibody will cross-react with Albumin, Due to the fact that BSA is used as the carrier, cGMP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
OVA conjugated cGMP |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Others |
| Cross Reactive Species details: |
cGMP |
| Background information: |
Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, Peptide hormones, Receptor activation of GC leads to the conversion of GTP to cGMP, Similar to cAMP, activate receptors that are associated with membrane-bound guanylate cyclase (GC), cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG), perhaps by binding to the heme moiety of the enzyme, such as the natriuretic factors, Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
JAW1L IRAG |
| Also known as: |
cGMP Polyclonal Antibody |
| Other name: |
Anti-cGMP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
cGMP |
| Short name: |
Anti-cGMP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-cGMP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7237 |
| Gene: |
MRVI1 |
More about : MRVI1 |
| Long gene name: |
murine retrovirus integration site 1 homolog |
| Synonyms name: |
inositol 1, 4, 5-triphosphate-associated cGMP kinase substrate IP3R-associated cGMP kinase substrate |
| Locus: |
11p15, 4 |
| Discovery year: |
1999-06-10 |
| GenBank acession: |
AF081249 |
| Entrez gene record: |
10335 |
| Pubmed identfication: |
10321731 |
| RefSeq identity: |
NM_001098579 |
| Havana BLAST/BLAT: |
OTTHUMG00000165773 |