| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SDH/Sorbitol Dehydrogenase |
| Specificity: |
This antibody reacts specifically with SDH/Sorbitol Dehydrogenase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Sorbitol Dehydrogenase |
| Gene ID: |
6390 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Although SORD is closely related to the class I long-chain alcohol dehydrogenases, SDH is expressed almost ubiquitously in all mammalian tissues, The enzyme has attracted considerable interest due to its implication in the development of diabetic complications as the polyol pathway is particularly active in hyperglycemic states, a member of the medium-chain dehydrogenase/reductase protein family and the second enzyme of the polyol pathway of glucose metabolism, catalyzing polyols such as sorbitol and xylitol but having no activity towards primary alcohols, converts sorbitol to fructose strictly using NAD(+) as coenzyme, it differs in substrate specificity, Sorbitol dehydrogenase (SDH) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SDH |
| Also known as: |
SDH/Sorbitol Dehydrogenase Antibody |
| Other name: |
Anti-SDH/Sorbitol Dehydrogenase |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
SDH/Sorbitol Dehydrogenase |
| Short name: |
Fluor 594, Anti-SDH/Sorbitol Dehydrogenase |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SDH/Sorbitol Dehydrogenase |
| Identity: |
10691 |
| Gene: |
SDS |
More about : SDS |
| Long gene name: |
serine dehydratase |
| Synonyms name: |
L-serine ammonia-lyase |
| Locus: |
12q24, 13 |
| Discovery year: |
1999-08-20 |
| GenBank acession: |
J05037 |
| Entrez gene record: |
10993 |
| Pubmed identfication: |
2674117 |
| RefSeq identity: |
NM_006843 |
| Havana BLAST/BLAT: |
OTTHUMG00000169554 |