| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Acetyl-Histone H4K12 |
| Specificity: |
This antibody reacts specifically with Acetyl-Histone H4(K12) |
| Modification: |
Acetylation |
| Modification site: |
K12 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic acetylpeptide derived from human Histone H4 around acetylation site of Lys12 |
| Gene ID: |
121504 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
H1, H2B, H3, Jul 2008], Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, The chromatin fiber is further compacted through the interaction of a linker histone, This gene is intronless and encodes a member of the histone H4 family, Transcripts from this gene lack polyA tails, [provided by RefSeq, and H4), instead, they contain a palindromic termination element, with the DNA between the nucleosomes to form higher order chromatin structures, Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
K12 |
| Also known as: |
Acetyl-Histone H4(K12) Antibody |
| Other name: |
Anti-Acetyl-Histone H4(K12) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Description: |
N terminal acetylation or CH3CO as epigenetic regulation of Anti- -Histone H4(K12) Fluor 594 by NATs |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Histone H4(K12) |
| Short name: |
Anti- -Histone H4(K12) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Acetyl-Histone H4(K12) |
| Identity: |
6414 |
| Gene: |
KRT12 |
More about : KRT12 |
| Long gene name: |
keratin 12 |
| Synonyms gene name: |
keratin 12, type I |
| Synonyms name: |
Meesmann corneal dystrophy |
| Locus: |
17q21, 2 |
| Discovery year: |
1997-07-22 |
| Entrez gene record: |
3859 |
| Pubmed identfication: |
9171831 16831889 |
| RefSeq identity: |
NM_000223 |
| Classification: |
Keratins, type I |
| Havana BLAST/BLAT: |
OTTHUMG00000133369 |