| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
p70 S6 Kinase Beta Thr444 + Ser447 |
| Specificity: |
This antibody reacts specifically with p70 S6 Kinase Beta (Thr444 + Ser447) |
| Modification: |
Phosphorylation |
| Modification site: |
Thr444 + Ser447 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human p70 S6 Kinase Beta around the phosphorylation site of Thr444/Ser447 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Activity of this gene has been associated with human cancer, Alternatively spliced transcript variants have been observed, Jan 2013], The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations, There are two pseudogenes for this gene on chromosome 17, [provided by RefSeq, and cell proliferation, cell growth, This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
70 kDa ribosomal protein S6 kinase 2, KS6B1_HUMAN, P70 S6 Kinase beta phospho T444 + S447, RPS6KB2, Ribosomal protein S6 kinase 70kDa, Ribosomal protein S6 kinase beta 2, Ribosomal protein S6 kinase beta-2, S6 kinase related kinase, S6 kinase-related kinase, S6K beta, S6K beta 2, S6K-beta, S6K2, SRK, STK14B, Serine/threonine protein kinase 14 beta, Serine/threonine-protein kinase 14 beta, p70 S6 kinase beta, p70 S6KB, p70 S6Kbeta, p70 beta, p70 ribosomal S6 kinase beta, p70-S6KB, p70-beta, p70S6K beta, p70S6Kb, polypeptide 2, p70 S6 KinaseThr444 + Ser447 |
| Also known as: |
p70 S6 Kinase Beta (Thr444 + Ser447) Antibody |
| Other name: |
Anti-p70 S6 Kinase Beta (Thr444 + Ser447) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
p70 S6 Kinase Beta (Thr444 + Ser447) |
| Short name: |
Anti-p70 S6 Kinase Beta (Thr444 + Ser447) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-p70 S6 phosphorylation catalyst b (Thr444 and Ser447) |