| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HRH3/GPCR97 |
| Specificity: |
This antibody reacts specifically with HRH3/GPCR97 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HRH3/GPCR97 |
| Gene ID: |
11255 |
| Swiss Prot: |
Q9Y5N1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization, Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist), The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GPCR97 |
| Also known as: |
HRH3/GPCR97 Polyclonal Antibody |
| Other name: |
Anti-HRH3/GPCR97 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HRH3/GPCR97 |
| Short name: |
Anti-HRH3/GPCR97 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-histamine receptor H3/GPCR97 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
GPCR97 and HH3R, HRH3 and IDBG-641005 and ENSBTAG00000031625 and 789851, HRH3 and IDBG-84247 and ENSG00000101180 and 11255, Hrh3 and IDBG-213755 and ENSMUSG00000039059 and 99296, Plasma membranes, coupled to cyclic nucleotide second messenger and biological process this GO :0007194 and negative regulation of adenylate cyclase activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0007420 and brain development and biological process this GO :0007612 and learning and biological process this GO :0007613 and memory and biological process this GO :0008144 and drug binding and molecular function this GO :0014050 and negative regulation of glutamate secretion and biological process this GO :0014053 and negative regulation of gamma-aminobutyric acid secretion and biological process this GO :0014061 and regulation of norepinephrine secretion and biological process this GO :0014063 and negative regulation of serotonin secretion and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0042755 and eating behavior and biological process this GO :0042756 and drinking behavior and biological process this GO :0043005 and neuron projection and cellular component this GO :0043209 and myelin sheath and cellular component this GO :0045776 and negative regulation of blood pressure and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050890 and cognition and biological process, drug binding, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004969 and histamine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007187 and G-protein coupled receptor signaling pathway, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004969 : histamine receptor activity and also this GO :0008144 : drug binding, this GO :0004969 : histamine receptor activity, this GO :0008144 : drug binding, histamine receptor H3 |
| Identity: |
5184 |
| Gene: |
HRH3 |
More about : HRH3 |
| Long gene name: |
histamine receptor H3 |
| Locus: |
20q13, 33 |
| Discovery year: |
2000-01-07 |
| GenBank acession: |
AF140538 |
| Entrez gene record: |
11255 |
| Pubmed identfication: |
10347254 |
| RefSeq identity: |
NM_007232 |
| Classification: |
Histamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000032899 |