| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
VASP |
| Specificity: |
This antibody reacts specifically with VASP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human VASP |
| Gene ID: |
7408 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions, In the mid-region of the protein, Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin, VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility, VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG, VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions, [provided by RefSeq], family members have a proline-rich domain that binds SH3 and WW domain-containing proteins, Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
VASP Polyclonal Antibody |
| Other name: |
Anti-VASP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
VASP |
| Short name: |
Anti-VASP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-VASP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12652 |
| Gene: |
VASP |
More about : VASP |
| Long gene name: |
vasodilator-stimulated phosphoprotein |
| Locus: |
19q13, 32 |
| Discovery year: |
1996-06-07 |
| Entrez gene record: |
7408 |
| Pubmed identfication: |
8812448 |
| Classification: |
ENAH/VASPs |
| Havana BLAST/BLAT: |
OTTHUMG00000182124 |