| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CXCR5/CD185 |
| Specificity: |
This antibody reacts specifically with CXCR5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Helical, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CXCR5 |
| Gene ID: |
643 |
| Swiss Prot: |
P32302 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes, May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation, Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MDR15 CD185 |
| Also known as: |
CXCR5 Polyclonal Antibody |
| Other name: |
Anti-CXCR5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CXCR5 |
| Short name: |
Anti-CXCR5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-chemokine (C-X-C motif) receptor 5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BLR1 and CD185 and MDR15, BLR1 and IDBG-631448 and ENSBTAG00000046320 and 497021, C-X-C chemokine receptor activity, CXCR5 and IDBG-74047 and ENSG00000160683 and 643, Cell surfaces, Cxcr5 and IDBG-157659 and ENSMUSG00000047880 and 12145, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0032467 and positive regulation of cytokinesis and biological process this GO :0042113 and B cell activation and biological process this GO :0048535 and lymph node development and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0005515 : protein binding and also this GO :0016494 : C-X-C chemokine receptor activity, this GO :0005515 : protein binding, this GO :0016494 : C-X-C chemokine receptor activity, chemokine (C-X-C motif) receptor 5 |
| Identity: |
1060 |
| Gene: |
CXCR5 |
More about : CXCR5 |
| Long gene name: |
C-X-C motif chemokine receptor 5 |
| Synonyms gene: |
BLR1 |
| Synonyms gene name: |
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) chemokine (C-X-C motif) receptor 5 , GTP-binding protein Burkitt lymphoma receptor 1 |
| Locus: |
11q23, 3 |
| Discovery year: |
1993-06-29 |
| GenBank acession: |
X68829 |
| Entrez gene record: |
643 |
| Pubmed identfication: |
1425907 |
| RefSeq identity: |
NM_001716 |
| Classification: |
CD molecules C-X-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000166345 |