| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Pyk2 Tyr881 |
| Specificity: |
This antibody reacts specifically with Pyk2 (Tyr881) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr881 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Pyk2 around the phosphorylation site of Tyr881 |
| Gene ID: |
2185 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Interacts with the SH2 domain of Grb2, May phosphorylate the voltage gated potassium channel protein Kv1, PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity, PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity, 2, PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CAK beta , CAKB antibody, CAKbeta, Calcium dependent tyrosine kinase, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, E430023O05Rik, EC 2, FADK 2, FADK2, FAK 2, FAK1, FAK2, Focal Adhesion Kinase 2, MGC124628, PKB, PTK 2B, PTK antibody PTK2B, PTK2B protein tyrosine kinase 2 beta, PYK 2, PYK2, Proline Rich Tyrosine Kinase 2, Proline-rich tyrosine kinase 2, Protein Tyrosine Kinase 2 Beta, Protein kinase B, RAFTK, Related adhesion focal tyrosine kinase, pp125FAK, 2, 7, 10, CADTK |
| Also known as: |
Pyk2 (Tyr881) Polyclonal Antibody |
| Other name: |
Anti-Pyk2 (Tyr881) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Pyk2 (Tyr881) |
| Short name: |
Anti-Pyk2 (Tyr881) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Pyk2 (Tyr881) (polyclonal) |
| Alternative technique: |
polyclonals |