| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PLC gamma 1 Tyr783 |
| Specificity: |
PLC gamma 1 (Tyr783), This phosphorylation site is homologous across the listed species |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr783 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr783 |
| Gene ID: |
5335 |
| Swiss Prot: |
P19174 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, FGFR1, FGFR2, FGFR3 and FGFR4, PDGFRB, Plays a role in actin reorganization and cell migration, Plays an important role in the regulation of intracellular signaling cascades, such as PDGFRA, 4, 5-trisphosphate (IP3), Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
1-phosphatidylinositol 4, NCKAP3, PLC-148, PLC-II, PLC-gamma-1, PLC148, PLCG1, PLCgamma1, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, Phospholipase C-gamma-1, 5-bisphosphate phosphodiesterase gamma-1, PLC1 |
| Also known as: |
PLC gamma 1 (Tyr783) Polyclonal Antibody |
| Other name: |
Anti-PLC gamma 1 (Tyr783) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PLC gamma 1 (Tyr783) |
| Short name: |
Anti-PLC gamma 1 (Tyr783) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PLC g 1 (Tyr783) (polyclonal) |
| Alternative technique: |
polyclonals |