| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IKK gamma Ser85 |
| Specificity: |
This antibody reacts specifically with IKK gamma (Ser85) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser85 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human IKK gamma around the phosphorylation site of Ser85 |
| Gene ID: |
8517 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A large, IKK alpha and Ikk beta, IKK gamma, IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex, IKK is composed of similar amounts of IKK alpha, Ikk beta, These subunits, an inhibitor of NF kappa B, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli, at sites that trigger its ubiquitination and degradation, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned, which are differentially processed forms of a third subunit, Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AMCBX1, FIP 3, FIP3, Fip3p, I kappa B kinase gamma, IKBKG, IKK Î, IKKÎ, IKKAP 1, IKKAP1, IKKG, IkB kinase associated protein 1, IkB kinase gamma subunit, IkB kinase subunit gamma, IkB kinase subunit gamma, Inhibitor of nuclear factor kappa B kinase subunit gamma, ³, ³, IkB kinase associated protein 1 |
| Also known as: |
IKK gamma (Ser85) Polyclonal Antibody |
| Other name: |
Anti-IKK gamma (Ser85) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IKK gamma (Ser85) |
| Short name: |
Anti-IKK gamma (Ser85) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-IKK g (Ser85) (polyclonal) |
| Alternative technique: |
polyclonals |