| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DOK2 Tyr142 |
| Specificity: |
This antibody reacts specifically with DOK2 (Tyr139) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr139 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human p56Dok2 around the phosphorylation site of Tyr139 |
| Gene ID: |
9046 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It may be a critical substrate for p210(bcr/abl), Jul 2008], This encoded protein binds p120 (RasGAP) from CML cells, [provided by RefSeq, a chimeric protein whose presence is associated with CML, The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
p56dok-2 Dok-2 |
| Also known as: |
DOK2 (Tyr139) Polyclonal Antibody |
| Other name: |
Anti-DOK2 (Tyr139) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DOK2 (Tyr139) |
| Short name: |
Anti-DOK2 (Tyr139) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DOK2 (Tyr139) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2991 |
| Gene: |
DOK2 |
More about : DOK2 |
| Long gene name: |
docking protein 2 |
| Synonyms gene name: |
56kD docking protein 2, 56kDa , docking protein 2 |
| Synonyms name: |
downstream of tyrosine kinase 2 |
| Locus: |
8p21, 3 |
| Discovery year: |
1999-02-05 |
| GenBank acession: |
AF034970 |
| Entrez gene record: |
9046 |
| Pubmed identfication: |
9478921 14645010 |
| RefSeq identity: |
NM_003974 |
| Havana BLAST/BLAT: |
OTTHUMG00000131075 |