| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ROM-K |
| Specificity: |
This antibody reacts specifically with ROM-K |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ROM-K/KCNJ1 |
| Gene ID: |
3758 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is activated by internal ATP and probably plays an important role in potassium homeostasis, Jul 2008], Multiple transcript variants encoding different isoforms have been found for this gene, Mutations in this gene have been associated with antenatal Bartter syndrome, The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell, The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, [provided by RefSeq, and low blood pressure, hypercalciuria, hypokalemic alkalosis, where they participate in a wide range of physiologic responses, which is characterized by salt wasting, Potassium channels are present in most mammalian cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ATP regulated potassium channel ROM K, ATP sensitive inward rectier potassium channel 1, ATP-regulated potassium channel ROM-K, ATP-sensitive inward rectier potassium channel 1, IRK1_HUMAN, Inward rectier K+ channel Kir1, KCNJ, KCNJ 1, Kcnj1, Kir 1, Kir1, Potassium channel, Potassium channel inwardly rectying subfamily J member 1, ROM-K, ROMK, ROMK 1, ROMK 2, ROMK1, ROMK2, inwardly rectying K+ channel, inwardly rectying subfamily J member 1, potassium inwardly-rectying channel J1, 1, 1, 1, ROM K |
| Also known as: |
ROM-K Polyclonal Antibody |
| Other name: |
Anti-ROM-K Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ROM-K |
| Short name: |
Anti-ROM-K (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ROM-K (polyclonal) |
| Alternative technique: |
polyclonals |