| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TNFRSF13B |
| Specificity: |
This antibody reacts specifically with TNFRSF13B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse TNFRSF13B |
| Gene ID: |
57916 |
| Swiss Prot: |
Q9ET35 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity (By similarity), Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1, Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TACI CD267 IGAD2 |
| Also known as: |
TNFRSF13B Polyclonal Antibody |
| Other name: |
Anti-TNFRSF13B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TNFRSF13B |
| Short name: |
Anti-TNFRSF13B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 13B (polyclonal), antibody to-tumor necrosis factor receptor superfamily |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CD267 and CVID and CVID2 and RYZN and TACI and TNFRSF14B, Cell surfaces, TNFRSF13B and IDBG-408940 and ENSG00000240505 and 23495, TNFRSF13B and IDBG-638376 and ENSBTAG00000015298 and, Tnfrsf13b and IDBG-182161 and ENSMUSG00000010142 and 57916, member 13B, protein binding, this GO :0001782 and B cell homeostasis and biological process this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0030889 and negative regulation of B cell proliferation and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, tumor necrosis factor receptor superfamily |
| Identity: |
18153 |
| Gene: |
TNFRSF13B |
More about : TNFRSF13B |
| Long gene name: |
TNF receptor superfamily member 13B |
| Synonyms gene name: |
member 13B , tumor necrosis factor receptor superfamily |
| Locus: |
17p11, 2 |
| Discovery year: |
2002-05-22 |
| GenBank acession: |
AF023614 |
| Entrez gene record: |
23495 |
| Pubmed identfication: |
9311921 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000059262 |
| Locus Specific Databases: |
TNFRSF13Bbase: Mutation registry for TACI deficiency LRG_120 |