| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Aurora C |
| Specificity: |
This antibody reacts specifically with Aurora C |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Aurora C |
| Gene ID: |
6795 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis, Aurora-C expression is maximum at M phase, Elevated expression levels are seen only in a subset of cancer cells such as HepG2, Expression is limited to testis in normal cells, HuH7 and HeLa cells, This protein is localized to centrosome from anaphase to cytokinesis, associate with microtubules during chromosome movement and segregation, members of the Ser/Thr protein kinase family, The Aurora kinases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AurC ARK3 |
| Also known as: |
Aurora C Polyclonal Antibody |
| Other name: |
Anti-Aurora C Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Aurora C |
| Short name: |
Anti-Aurora C (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Aurora C (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11391 |
| Gene: |
AURKC |
More about : AURKC |
| Long gene name: |
aurora kinase C |
| Synonyms gene: |
STK13 |
| Synonyms gene name: |
serine/threonine kinase 13 (aurora/IPL1-like) |
| Locus: |
19q13, 43 |
| Discovery year: |
1998-05-13 |
| Entrez gene record: |
6795 |
| Pubmed identfication: |
9799611 |
| RefSeq identity: |
NM_003160 |
| Havana BLAST/BLAT: |
OTTHUMG00000183106 |