| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Plexin A1 |
| Specificity: |
This antibody reacts specifically with Plexin A1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Plexin A1 |
| Gene ID: |
5361 |
| Swiss Prot: |
Q9UIW2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin, Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton, Plays a role in axon guidance, SEMA3C, SEMA3F and SEMA6D, The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity), invasive growth and cell migration, Coreceptor for SEMA3A |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NOV |
| Also known as: |
Plexin A1 Polyclonal Antibody |
| Other name: |
Anti-Plexin A1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Plexin A1 |
| Short name: |
Anti-Plexin A1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Plexin A1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9099 |
| Gene: |
PLXNA1 |
More about : PLXNA1 |
| Long gene name: |
plexin A1 |
| Synonyms gene: |
PLXN1 |
| Locus: |
3q21, 3 |
| Discovery year: |
1998-08-13 |
| GenBank acession: |
X87832 |
| Entrez gene record: |
5361 |
| Pubmed identfication: |
8570614 |
| RefSeq identity: |
NM_032242 |
| Classification: |
Plexins |
| Havana BLAST/BLAT: |
OTTHUMG00000044222 |