| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IL-3R alpha/CD123 |
| Specificity: |
This antibody reacts specifically with IL-3R alpha/CD123 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IL-3R alpha |
| Gene ID: |
3563 |
| Swiss Prot: |
P26951 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
The beta subunit is activated by the ligand binding, The binding of this protein to IL3 depends on the beta subunit, The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y, and interleukin 5 (IL5), and is required for the biological activities of IL3, colony stimulating factor 2 (CSF2/GM-CSF), The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD123 |
| Also known as: |
IL-3R alpha/CD123 Polyclonal Antibody |
| Other name: |
Anti-IL-3R alpha/CD123 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IL-3R alpha/CD123 |
| Short name: |
Anti-IL-3R alpha/CD123 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Interleukin-3R a/CD123 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6012 |
| Gene: |
IL3RA |
More about : IL3RA |
| Long gene name: |
interleukin 3 receptor subunit alpha |
| Synonyms gene name: |
alpha (low affinity) , interleukin 3 receptor |
| Locus: |
Xp22, 3 , 3 and Yp13 |
| Discovery year: |
1992-10-28 |
| GenBank acession: |
M74782 |
| Entrez gene record: |
3563 |
| Pubmed identfication: |
1833064 |
| Classification: |
CD molecules Pseudoautosomal region 1 Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000021059 |