| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IGSF8/CD316 |
| Specificity: |
This antibody reacts specifically with IGSF8/CD316 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse IGSF8 |
| Gene ID: |
140559 |
| Swiss Prot: |
Q8R366 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
May also play a role on integrin-dependent morphology and motility functions, May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain, May regulate proliferation and differentiation of keratinocytes, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers, May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD81P3 EWI2 PGRL CD316 |
| Also known as: |
IGSF8/CD316 Polyclonal Antibody |
| Other name: |
Anti-IGSF8/CD316 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IGSF8/CD316 |
| Short name: |
Anti-IGSF8/CD316 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 8/CD316 (polyclonal), antibody to-immunoglobulin superfamily |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
IGSF8 and IDBG-103984 and ENSG00000162729 and 93185, IGSF8 and IDBG-630653 and ENSBTAG00000009982 and 519266, Igsf8 and IDBG-205334 and ENSMUSG00000038034 and 140559, Plasma membranes, member 8, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006928 and cellular component movement and biological process this GO :0007338 and single fertilization and biological process this GO :0007399 and nervous system development and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding, immunoglobulin superfamily |
| Identity: |
17813 |
| Gene: |
IGSF8 |
More about : IGSF8 |
| Long gene name: |
immunoglobulin superfamily member 8 |
| Synonyms gene name: |
immunoglobulin superfamily, member 8 |
| Locus: |
1q23, 2 |
| Discovery year: |
2002-01-08 |
| GenBank acession: |
AF407274 |
| Entrez gene record: |
93185 |
| Pubmed identfication: |
11504738 11673522 |
| RefSeq identity: |
NM_052868 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000024075 |