| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CXCL13/BCA1 |
| Specificity: |
This antibody reacts specifically with CXCL13 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CXCL13 |
| Gene ID: |
10563 |
| Swiss Prot: |
O43927 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds to BLR1/CXCR5, Does not induce calcium release in B-lymphocytes, monocytes and neutrophils, Chemotactic for B-lymphocytes but not for T-lymphocytes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BLC BCA-1 BLR1L ANGIE ANGIE2 |
| Also known as: |
CXCL13 Polyclonal Antibody |
| Other name: |
Anti-CXCL13 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CXCL13 |
| Short name: |
Anti-CXCL13 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-chemokine (C-X-C motif) ligand 13 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ANGIE and ANGIE2 and BCA-1 and BCA1 and BLC and BLR1L and SCYB13, CXCL13 and IDBG-25774 and ENSG00000156234 and 10563, CXCL13 and IDBG-643139 and ENSBTAG00000008479 and 511674, CXCR3 chemokine receptor binding, Cxcl13 and IDBG-181227 and ENSMUSG00000023078 and 55985, Extracellular, this GO :0002467 and germinal center formation and biological process this GO :0002518 and lymphocyte chemotaxis across high endothelial venule and biological process this GO :0002544 and chronic inflammatory response and biological process this GO :0002920 and regulation of humoral immune response and biological process this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0010820 and positive regulation of T cell chemotaxis and biological process this GO :0017134 and fibroblast growth factor binding and molecular function this GO :0031724 and CXCR5 chemokine receptor binding and molecular function this GO :0031735 and CCR10 chemokine receptor binding and molecular function this GO :0032861 and activation of Rap GTPase activity and biological process this GO :0033625 and positive regulation of integrin activation and biological process this GO :0033634 and positive regulation of cell-cell adhesion mediated by integrin and biological process this GO :0035754 and B cell chemotaxis and biological process this GO :0035768 and endothelial cell chemotaxis to fibroblast growth factor and biological process this GO :0035769 and B cell chemotaxis across high endothelial venule and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048018 and receptor a this GO nist activity and molecular function this GO :0048248 and CXCR3 chemokine receptor binding and molecular function this GO :0048535 and lymph node development and biological process this GO :2000545 and negative regulation of endothelial cell chemotaxis to fibroblast growth factor and biological process, this GO :0008009 : chemokine activity, this GO :0008009 : chemokine activity and also this GO :0008201 : heparin binding and also this GO :0017134 : fibroblast growth factor binding and also this GO :0031724 : CXCR5 chemokine receptor binding and also this GO :0031735 : CCR10 chemokine receptor binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0048018 : receptor a this GO nist activity and also this GO :0048248 : CXCR3 chemokine receptor binding, this GO :0008201 : heparin binding, this GO :0017134 : fibroblast growth factor binding, this GO :0031724 : CXCR5 chemokine receptor binding, this GO :0031735 : CCR10 chemokine receptor binding, this GO :0046982 : protein heterodimerization activity, this GO :0048018 : receptor a this GO nist activity, this GO :0048248 : CXCR3 chemokine receptor binding, chemokine (C-X-C motif) ligand 13 |
| Identity: |
10639 |
| Gene: |
CXCL13 |
More about : CXCL13 |
| Long gene name: |
C-X-C motif chemokine ligand 13 |
| Synonyms gene: |
SCYB13 |
| Synonyms gene name: |
member 13 (B-cell chemoattractant) chemokine (C-X-C motif) ligand 13 , small inducible cytokine B subfamily (Cys-X-Cys motif) |
| Synonyms name: |
B-cell chemoattractant |
| Locus: |
4q21, 1 |
| Discovery year: |
2000-09-05 |
| GenBank acession: |
AJ002211 |
| Entrez gene record: |
10563 |
| Pubmed identfication: |
9463416 9486651 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000130201 |