| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AQP7 |
| Specificity: |
This antibody reacts specifically with AQP7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AQP7 |
| Gene ID: |
364 |
| Swiss Prot: |
O14520 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
268aa, 28kD, AQP0 or MIP26 (major intrinsic protein 26kD), Defects in MIP26 are cause of autosomal dominant cataract, Interestingly, Mammalian red cells, Over the last decade, The cataract Fraser mutation (CATFR or Shriveled) is a transposon induced splicing error that substitutes a long terminal repeat sequence for the C terminus of MIP, The lens opacity mutation (LOP) is an amino acid substitution that inhibits targeting of MIP to the cell membrane, The lens specific AQP0 represents up to 80% of total lens membrane protein, Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein ", and Aquaporin 1 (AQP1, and descending thin limb of Henle are extraordinarily permeable to water, and their distribution studied in many tissues, expressed, gene locus 7p14) has been the foundation of the growing family of aquaporin, genes for several members of aquaporin family have been cloned, purified from red cells) also called CHIP28 (channel forming integral protein, renal proximal tubules, tissue membranes show a great degree of water permeability, Water is a critical component of all living cells, aquaporin" |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AQP9 AQPap |
| Also known as: |
AQP7 Polyclonal Antibody |
| Other name: |
Anti-AQP7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AQP7 |
| Short name: |
Anti-AQP7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-AQP7 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
640 |
| Gene: |
AQP7 |
More about : AQP7 |
| Long gene name: |
aquaporin 7 |
| Synonyms gene: |
AQP7L |
| Locus: |
9p13, 3 |
| Discovery year: |
1997-04-10 |
| GenBank acession: |
AB006190 |
| Entrez gene record: |
364 |
| Pubmed identfication: |
9252401 |
| RefSeq identity: |
NM_001170 |
| Classification: |
Aquaporins |
| Havana BLAST/BLAT: |
OTTHUMG00000019773 |