| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TNFSF18 |
| Specificity: |
This antibody reacts specifically with TNFSF18 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TNFSF18 |
| Gene ID: |
8995 |
| Swiss Prot: |
Q9UNG2 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation, Important for interactions between activated T-lymphocytes and endothelial cells, Mediates activation of NF-kappa-B, Regulates T-cell responses, Cytokine that binds to TNFRSF18/AITR/GITR |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AITRL TL6 hGITRL |
| Also known as: |
TNFSF18 Polyclonal Antibody |
| Other name: |
Anti-TNFSF18 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TNFSF18 |
| Short name: |
Anti-TNFSF18 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 18 (polyclonal), antibody to-tumor necrosis factor (ligand) superfamily |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AITRL and GITRL and hGITRL and TL6, Extracellular, LOC768081 and IDBG-632315 and ENSBTAG00000047412 and 768081, TNFSF18 and IDBG-104861 and ENSG00000120337 and 8995, Tnfsf18 and IDBG-201543 and ENSMUSG00000066755 and 240873, member 18, this GO :0002309 and T cell proliferation involved in immune response and biological process this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032813 and tumor necrosis factor receptor superfamily binding and molecular function this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042129 and regulation of T cell proliferation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0032813 : tumor necrosis factor receptor superfamily binding, this GO :0005125 : cytokine activity, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, this GO :0032813 : tumor necrosis factor receptor superfamily binding, tumor necrosis factor receptor superfamily binding, tumor necrosis factor (ligand) superfamily |
| Identity: |
11932 |
| Gene: |
TNFSF18 |
More about : TNFSF18 |
| Long gene name: |
tumor necrosis factor superfamily member 18 |
| Synonyms gene name: |
member 18 , tumor necrosis factor (ligand) superfamily |
| Locus: |
1q25, 1 |
| Discovery year: |
1999-01-15 |
| GenBank acession: |
AF117713 |
| Entrez gene record: |
8995 |
| Pubmed identfication: |
10037686 10074428 |
| RefSeq identity: |
NM_005092 |
| Classification: |
Tumor necrosis factor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000034835 |