| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Coxsackie Adenovirus Receptor |
| Specificity: |
This antibody reacts specifically with Coxsackie Adenovirus Receptor |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor |
| Gene ID: |
1525 |
| Swiss Prot: |
P78310 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases, Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes, It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair, The interaction between both receptors also mediates the activation of gamma-delta T-cells, Upon epithelial CXADR-binding, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair, Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CAR4/6, CVB3-binding protein, CXADR, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor, HCAR, HCVADR, CAR |
| Also known as: |
Coxsackie Adenovirus Receptor Antibody |
| Other name: |
Anti-Coxsackie Adenovirus Receptor |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Coxsackie Adenovirus Receptor |
| Short name: |
Fluor 594, Anti-Coxsackie Adenovirus Receptor |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Coxsackie Adenovirus Receptor |