| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Angiotensin II Type 1 Receptor |
| Specificity: |
This antibody reacts specifically with Angiotensin II Type 1 Receptor |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AT1R |
| Gene ID: |
185 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additional variants have been described but their full-length nature has not been determined, At least five transcript variants have been described for this gene, It acts through at least two types of receptors, It is an important effector controlling blood pressure and volume in the cardiovascular system, It was previously thought that a related gene, The entire coding sequence is contained in the terminal exon and is present in all transcript variants, This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II, This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium, [provided by RefSeq], denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans, Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AGTR1B, AGTR1_HUMAN, AT 1B, AT-1B, AT-1r, AT1, AT1, AT1AR, AT1B, AT1BR, AT1R, AT1R, AT2R1, AT2R1A, AT2R1B, Agtr 1, Agtr1, Agtr1a, Ang II, Angiotensin II receptor type 1, Angiotensin II receptor type 1, Angiotensin II type 1 receptor, Angiotensin II type 1 receptor, Angiotensin II type-1 receptor, Angiotensin receptor 1, Angiotensin receptor 1B, At1a, HAT1R, Type 1 angiotensin II receptor, Type-1 angiotensin II receptor, AG2S |
| Also known as: |
Angiotensin II Type 1 Receptor Antibody |
| Other name: |
Anti- Angiotensin II Type 1 Receptor |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Angiotensin II 1 Receptor |
| Short name: |
Fluor 594, Anti- Angiotensin II 1 Receptor |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, Antibody to Angiotensin II classification 1 Receptor |