| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LPL/PLASTIN2 |
| Specificity: |
This antibody reacts specifically with LPL/PLASTIN2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LPL |
| Gene ID: |
4023 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects, Recently, The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation, Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
LPL/PLASTIN2 Polyclonal Antibody |
| Other name: |
Anti-LPL/PLASTIN2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LPL/PLASTIN2 |
| Short name: |
Anti-LPL/PLASTIN2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-lipoprotein lipase/PLASTIN2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Extracellular, HDLCQ11 and LIPD, LPL and IDBG-634385 and ENSBTAG00000012855 and 280843, LPL and IDBG-9632 and ENSG00000175445 and 4023, Lpl and IDBG-159560 and ENSMUSG00000015568 and 16956, carboxylic ester hydrolase activity, this GO :0001523 and retinoid metabolic process and biological process this GO :0004465 and lipoprotein lipase activity and molecular function this GO :0004620 and phospholipase activity and molecular function this GO :0004806 and triglyceride lipase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006633 and fatty acid biosynthetic process and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0007603 and phototransduction, this GO :0004465 : lipoprotein lipase activity, this GO :0004465 : lipoprotein lipase activity and also this GO :0004620 : phospholipase activity and also this GO :0004806 : triglyceride lipase activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008201 : heparin binding and also this GO :0017129 : triglyceride binding and also this GO :0034185 : apolipoprotein binding and also this GO :0052689 : carboxylic ester hydrolase activity, this GO :0004620 : phospholipase activity, this GO :0004806 : triglyceride lipase activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0008201 : heparin binding, this GO :0017129 : triglyceride binding, this GO :0034185 : apolipoprotein binding, this GO :0052689 : carboxylic ester hydrolase activity, visible light and biological process this GO :0008201 and heparin binding and molecular function this GO :0009409 and response to cold and biological process this GO :0009986 and cell surface and cellular component this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0010886 and positive regulation of cholesterol storage and biological process this GO :0010890 and positive regulation of sequestering of triglyceride and biological process this GO :0016042 and lipid catabolic process and biological process this GO :0017129 and triglyceride binding and molecular function this GO :0019432 and triglyceride biosynthetic process and biological process this GO :0019433 and triglyceride catabolic process and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0031225 and anchored component of membrane and cellular component this GO :0034185 and apolipoprotein binding and molecular function this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034371 and chylomicron remodeling and biological process this GO :0034372 and very-low-density lipoprotein particle remodeling and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042627 and chylomicron and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0052689 and carboxylic ester hydrolase activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process, lipoprotein lipase |
| Identity: |
6677 |
| Gene: |
LPL |
More about : LPL |
| Long gene name: |
lipoprotein lipase |
| Synonyms gene: |
LIPD |
| Locus: |
8p21, 3 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
4023 |
| Pubmed identfication: |
3823907 3597382 3692485 |
| Classification: |
Lipases |
| Havana BLAST/BLAT: |
OTTHUMG00000036645 |