| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
FITC |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IRAK1BP1 |
| Specificity: |
IRAK1BP1 FITC, This antibody may exhibit a minor secondary cross-reactivity with SMPD5 due to a 63% contiguous sequence similarity over the immunogen range |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IRAK1BP1 |
| Gene ID: |
134728 |
| Swiss Prot: |
Q5VVH5 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts by enhancing RELA transcriptional activity (By similarity), Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
494nm/518nm |
| Synonyms: |
AIP70 SIMPL |
| Also known as: |
IRAK1BP1 Polyclonal Antibody FITC |
| Other name: |
Anti-IRAK1BP1 Polyclonal FITC |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
Bioss Polyclonal Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This Bioss Polyclonal Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation: |
Anti-FITC Antibody |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IRAK1BP1 |
| Short name: |
Anti-IRAK1BP1 (Polyclonal) FITC |
| Technique: |
Fluorescein, Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
FITC |
| Alternative name: |
fluorecein, antibody to-interleukin-1 receptor-associated phosphorylation catalyst 1 binding protein 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process, IRAK1BP1 and IDBG-630000 and ENSBTAG00000020825 and 782235, IRAK1BP1 and IDBG-93345 and ENSG00000146243 and 134728, Irak1bp1 and IDBG-188214 and ENSMUSG00000032251 and 65099, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0005515 : protein binding, this GO :0005515 : protein binding, interleukin-1 receptor-associated kinase 1 binding protein 1 |
| Identity: |
17368 |
| Gene: |
IRAK1BP1 |
More about : IRAK1BP1 |
| Long gene name: |
interleukin 1 receptor associated kinase 1 binding protein 1 |
| Locus: |
6q14, 1 |
| Discovery year: |
2003-07-17 |
| GenBank acession: |
AI478629 |
| Entrez gene record: |
134728 |
| Pubmed identfication: |
11096118 |
| RefSeq identity: |
XM_059729 |
| Havana BLAST/BLAT: |
OTTHUMG00000015070 |