| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HERPUD1 |
| Specificity: |
This antibody reacts specifically with HERPUD1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HERPUD1 |
| Gene ID: |
9709 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing of this gene produces multiple transcript variants encoding different isoforms, Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system, Jan 2013], The full-length nature of all transcript variants has not been determined, This gene may play a role in both UPR and ERAD, This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression, [provided by RefSeq, and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system, known as the unfolded protein response (UPR), the increased expression of proteins involved in polypeptide folding, HERPUD1 is a includes the inhibition of translation to prevent further accumulation of unfolded proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0025 Mif1 HERP SUP |
| Also known as: |
HERPUD1 Polyclonal Antibody |
| Other name: |
Anti-HERPUD1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HERPUD1 |
| Short name: |
Anti-HERPUD1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 (polyclonal), antibody to-homocysteine-inducible |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, HERP and Mif1 and SUP, HERPUD1 and IDBG-32578 and ENSG00000051108 and 9709, Herpud1 and IDBG-182026 and ENSMUSG00000031770 and 64209, Plasma membranes, endoplasmic reticulum stress-inducible, protein binding, this GO :0003674 and molecular function and molecular function this GO :0005515 and protein binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006986 and response to unfolded protein and biological process this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031396 and regulation of protein ubiquitination and biological process this GO :0032092 and positive regulation of protein binding and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044267 and cellular protein metabolic process and biological process, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, ubiquitin-like domain member 1, 105012 and IDBG-632267 and ENSBTAG00000016896 and 613577, homocysteine-inducible |
| Identity: |
13744 |
| Gene: |
HERPUD1 |
More about : HERPUD1 |
| Long gene name: |
homocysteine inducible ER protein with ubiquitin like domain 1 |
| Synonyms gene name: |
endoplasmic reticulum stress-inducible, homocysteine-inducible, ubiquitin-like domain member 1 |
| Locus: |
16q13 |
| Discovery year: |
2000-11-29 |
| GenBank acession: |
AB034989 |
| Entrez gene record: |
9709 |
| Pubmed identfication: |
10922362 10708769 |
| Havana BLAST/BLAT: |
OTTHUMG00000133276 |