| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AP-TNAP/ALPL |
| Specificity: |
This antibody reacts specifically with AP-TNAP/ALPL |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane |
| Antigen Source: |
KLH conjugated synthetic peptide derived from AP-TNAP/ALPL |
| Gene ID: |
11647 |
| Swiss Prot: |
P09242 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Damaged or diseased tissue releases enzymes into the blood, Most mammals have 4 different isozymes: placental, Tissues with particularly high concentrations of ALP include the liver, and bone, and from proteins, at high pH, bile ducts, including bone disease and liver disease, intestinal and non tissue specific (found in liver, kidney and bone), placenta, placental like, so serum ALP measurements can be abnormal in many conditions, Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AP-TNAP, APTNAP, Akp-2, Alkaline phosphatase, Alkaline phosphatase 2, Alkaline phosphatase liver/bone/kidney isozyme, Alpl, TNAP, TNSALP, tissue-nonspecific isozyme, Akp2 |
| Also known as: |
AP-TNAP/ALPL Polyclonal Antibody |
| Other name: |
Anti-AP-TNAP/ALPL Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AP-TNAP/ALPL |
| Short name: |
Anti-AP-TNAP/ALPL (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
AP |
| Alternative name: |
ALEXA Fluor 594, liver/bone/kidney (polyclonal), antibody to-AP-TNAP/alkaline phosphatase |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ALPL and IDBG-645614 and ENSBTAG00000008951 and 280994, ALPL and IDBG-93194 and ENSG00000162551 and 249, AP-TNAP and APTNAP and HOPS and TNAP and TNSALP, Alpl and IDBG-199139 and ENSMUSG00000028766 and 11647, Extracellular, liver/bone/kidney, metal ion binding, this GO :0001501 and skeletal system development and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001958 and endochondral ossification and biological process this GO :0003006 and developmental process involved in reproduction and biological process this GO :0003824 and catalytic activity and molecular function this GO :0004035 and alkaline phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0008152 and metabolic process and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016462 and pyrophosphatase activity and molecular function this GO :0016791 and phosphatase activity and molecular function this GO :0031012 and extracellular matrix and cellular component this GO :0031225 and anchored component of membrane and cellular component this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033280 and response to vitamin D and biological process this GO :0046677 and response to antibiotic and biological process this GO :0046872 and metal ion binding and molecular function this GO :0051384 and response to glucocorticoid and biological process this GO :0065010 and extracellular membrane-bounded organelle and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071529 and cementum mineralization and biological process, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004035 : alkaline phosphatase activity and also this GO :0005515 : protein binding and also this GO :0016462 : pyrophosphatase activity and also this GO :0016791 : phosphatase activity and also this GO :0046872 : metal ion binding, this GO :0004035 : alkaline phosphatase activity, this GO :0005515 : protein binding, this GO :0016462 : pyrophosphatase activity, this GO :0016791 : phosphatase activity, this GO :0046872 : metal ion binding, alkaline phosphatase |