| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ATRN |
| Specificity: |
This antibody reacts specifically with ATRN |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ATRN |
| Gene ID: |
8455 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Attractinmay be a component of a pathway for regulated protein turnover that also involves mahogunin, Attractinwas considered as an extracellular target amenable for the development of obesity-regulating drugs, Both the secreted and membrane-bound forms of attractin may be involved in the development and maintenance of the central nervous system, Membrane-bound attractin is a co-receptor for Agouti, Secreted attractin, a wide-expressed E3 ubiquitinligase found at particularly high levels in the brain, also, antagonist of melanocortin-1 receptor, expressed by activated T lymphocytes and modulates interactions between T cells and monocytes/macrophages, was examined as a potential marker of immune activity, Attractin is a serum glycoprotein of 175 kDaand found in both membrane-bound and secreted forms as a result of alternative splicing |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DPPT-L MGCA |
| Also known as: |
ATRN Polyclonal Antibody |
| Other name: |
Anti-ATRN Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ATRN |
| Short name: |
Anti-ATRN (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ATRN (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
885 |
| Gene: |
ATRN |
More about : ATRN |
| Long gene name: |
attractin |
| Synonyms name: |
mahogany protein |
| Locus: |
20p13 |
| Discovery year: |
1998-10-30 |
| GenBank acession: |
AF034957 |
| Entrez gene record: |
8455 |
| Pubmed identfication: |
9736737 8596018 |
| RefSeq identity: |
NM_139321 |
| Classification: |
C-type lectin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031746 |