| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Cathepsin L |
| Specificity: |
This antibody reacts specifically with Cathepsin L |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Lysosome |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse capsin L1 proprotein |
| Gene ID: |
13039 |
| Swiss Prot: |
P06797 |
| Applications: |
IF(ICC), IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
At least two transcript variants encoding the same protein have been found for this gene, Its substrates include collagen and elastin, The encoded protein has been implicated in several pathologic processes, This protein, a major controlling element of neutrophil elastase activity, and in the renal tubular response to proteinuria, as well as alpha-1 protease inhibitor, both produced from a single protein precursor, including myofibril necrosis in myopathies and in myocardial ischemia, is a dimer composed of disulfide-linked heavy and light chains, which is a member of the peptidase C1 family, The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HCTSL-s |
| Also known as: |
Cathepsin L Polyclonal Antibody |
| Other name: |
Anti-Cathepsin L Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene: |
CTSL3P |
More about : CTSL3P |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Cathepsin L |
| Short name: |
Anti-Cathepsin L (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cathepsin L (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
33132 |
| Long gene name: |
cathepsin L family member 3, pseudogene |
| Synonyms gene: |
CTSL3 |
| Synonyms gene name: |
cathepsin L family member 3 |
| Locus: |
9q21, 33 |
| Discovery year: |
2007-04-27 |
| GenBank acession: |
AJ851862 |
| Entrez gene record: |
392360 |
| Pubmed identfication: |
19663681 |
| RefSeq identity: |
NR_027917 |
| Havana BLAST/BLAT: |
OTTHUMG00000020152 |